PILO, Maria Giulia
PILO, Maria Giulia
Universita' degli Studi di SASSARI
A functional mammalian target of rapamycin complex 1 signaling is indispensable for c-Myc-driven hepatocarcinogenesis
2017-01-01 Liu, Pin; Ge, Mengmeng; Hu, Junjie; Li, Xiaolei; Che, Li; Sun, Kun; Cheng, Lili; Huang, Yuedong; Pilo, Maria G; Cigliano, Antonio; Pes, Giovanni M; Pascale, Rosa M; Brozzetti, Stefania; Vidili, Gianpaolo; Porcu, Alberto; Cossu, Antonio; Palmieri, Giuseppe; Sini, Maria C; Ribback, Silvia; Dombrowski, Frank; Tao, Junyan; Calvisi, Diego F; Chen, Ligong; Chen, Xin
Activated mutant forms of PIK3CA cooperate with RasV12 or c-Met to induce liver tumour formation in mice via AKT2/mTORC1 cascade
2016-01-01 Wang, Chunmei; Che, Li; Hu, Junjie; Zhang, Shanshan; Jiang, Lijie; Latte, Gavinella; Demartis, Maria Ilaria; Tao, Junyan; Gui, Bing; Pilo, Maria Giulia; Ribback, Silvia; Dombrowski, Frank; Evert, Matthias; Calvisi, Diego Francesco; Chen, Xin
Both de novo synthetized and exogenous fatty acids support the growth of hepatocellular carcinoma cells
2017-01-01 Cao, Dan; Song, Xinhua; Che, Li; Li, Xiaolei; Pilo, Maria G.; Vidili, Gianpaolo; Porcu, Alberto; Solinas, Antonio; Cigliano, Antonio; Pes, Giovanni M.; Ribback, Silvia; Dombrowski, Frank; Chen, Xin; Li, Lei; Calvisi, Diego F.
Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans
2019-01-01 Che, Li; Chi, Wenna; Qiao, Yu; Zhang, Jie; Song, Xinhua; Liu, Ye; Li, Lei; Jia, Jiaoyuan; Pilo, Maria G.; Wang, Jingxiao; Cigliano, Antonio; Ma, Zhilong; Kuang, Wenhua; Tang, Zefang; Zhang, Zemin; Shui, Guanghou; Ribback, Silvia; Dombrowski, Frank; Evert, Matthias; Pascale, Rosa Maria; Cossu, Carla; Pes, Giovanni Mario; Osborne, Timothy F.; Calvisi, Diego F.; Chen, Xin; Chen, Ligong
Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice
2016-01-01 Hu, Junjie; Che, Li; Li, Lei; Pilo, Maria Giulia; Cigliano, Antonio; Ribback, Silvia; Li, Xiaolei; Latte, Gavinella; Mela, Marta; Evert, Matthias; Dombrowski, Frank; Zheng, Guohua; Chen, Xin; Calvisi, Diego Francesco
Deregulated c-Myc requires a functional HSF1 for experimental and human hepatocarcinogenesis
2017-01-01 Cigliano, Antonio; Pilo, Maria G.; Li, Lei; Latte, Gavinella; Szydlowska, Marta; Simile, Maria M.; Paliogiannis, Panagiotis; Che, Li; Pes, Giovanni M.; Palmieri, Giuseppe; Sini, Maria C.; Cossu, Antonio; Porcu, Alberto; Vidili, Gianpaolo; Seddaiu, Maria A.; Pascale, Rosa M.; Ribback, Silvia; Dombrowski, Frank; Chen, Xin; Calvisi, Diego F.
Differential requirement for de novo lipogenesis in cholangiocarcinoma and hepatocellular carcinoma of mice and humans
2016-01-01 Li, Lei; Che, Li; Tharp, Kevin M.; Park, Hyo Min; Pilo, Maria Giulia; Cao, Dan; Cigliano, Antonio; Latte, Gavinella; Xu, Zhong; Ribback, Silvia; Dombrowski, Frank; Evert, Matthias; Gores, Gregory J.; Stahl, Andreas; Calvisi, Diego Francesco; Chen, Xin
Inhibition of HSF1 suppresses the growth of hepatocarcinoma cell lines in vitro and AKT-driven hepatocarcinogenesis in mice
2017-01-01 Cigliano, Antonio; Wang, Chunmei; Pilo, Maria Giulia; Szydlowska, Marta; Brozzetti, Stefania; Latte, Gavinella; Pes, Giovanni Mario; Pascale, Rosa Maria; Seddaiu, Maria Antonietta; Vidili, Gianpaolo; Ribback, Silvia; Dombrowski, Frank; Evert, Matthias; Chen, Xin; Calvisi, Diego Francesco
Inhibition of MELK Protooncogene as an Innovative Treatment for Intrahepatic Cholangiocarcinoma
2020-01-01 Cigliano, Antonio; Pilo, Maria Giulia; Mela, Marta; Ribback, Silvia; Dombrowski, Frank; Pes, Giovanni Mario; Cossu, Antonio; Evert, Matthias; Calvisi, Diego Francesco; Utpatel, Kirsten
Jagged 1 is a major Notch ligand along cholangiocarcinoma development in mice and humans
2016-01-01 Che, L.; Fan, B.; Pilo, Maria Giulia; Xu, Z.; Liu, Yisu; Cigliano, Antonio; Cossu, Antonio; Palmieri, Giovanni; Pascale, Rosa Maria; Porcu, Alberto; Vidili, Gianpaolo; Serra, Marina; Dombrowski, F.; Ribback, S.; Calvisi, Diego Francesco; Chen, X.
La Completa inibizione della via di segnale mTORC1 è necessaria per la soppressione dell’epatocancerogenesi indotta dall’iperespressione dei protooncogeni AKT e N-Ras nel topo
2014-02-24 Pilo, Maria Giulia
Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma
2017-01-01 Che, Li; Pilo, Maria Giulia; Cigliano, Antonio; Latte, Gavinella; Simile, Maria Maddalena; Ribback, Silvia; Dombrowski, Frank; Evert, Matthias; Chen, Xin; Calvisi, Diego Francesco
Oncogene-dependent addiction to carbohydrate-responsive element binding protein in hepatocellular carcinoma
2018-01-01 Ribback, S; Che, L; Pilo, Mg; Cigliano, A; Latte, G; Pes, Gm; Porcu, A; Pascale, Rm; Li, L; Qiao, Yan; Dombrowski, F; Chen, X; Calvisi, Df
Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice
2017-01-01 Zhang, Shanshan; Song, Xinhua; Cao, Dan; Xu, Zhong; Fan, Biao; Che, Li; Hu, Junjie; Chen, Bin; Dong, Mingjie; Pilo, Maria G.; Cigliano, Antonio; Evert, Katja; Ribback, Silvia; Dombrowski, Frank; Pascale, Rosa M.; Cossu, Antonio; Vidili, Gianpaolo; Porcu, Alberto; Simile, Maria M.; Pes, Giovanni M.; Giannelli, Gianluigi; Gordan, John; Wei, Lixin; Evert, Matthias; Cong, Wenming; Calvisi, Diego F.; Chen, Xin
Pathogenetic, Prognostic, and Therapeutic Role of Fatty Acid Synthase in Human Hepatocellular Carcinoma
2019-01-01 Che, Li; Paliogiannis, Panagiotis; Cigliano, Antonio; Pilo, Maria G.; Chen, Xin; Calvisi, Diego F.
Tankyrase inhibitors suppress hepatocellular carcinoma cell growth via modulating the Hippo cascade
2017-01-01 Jia, J.; Qiao, Y.; Pilo, M. G.; Cigliano, A.; Liu, X.; Shao, Z.; Calvisi, D. F.; Chen, X.
The Epidermal Growth Factor Receptor (EGFR) Inhibitor Gefitinib Reduces but Does Not Prevent Tumorigenesis in Chemical and Hormonal Induced Hepatocarcinogenesis Rat Models
2016-01-01 Ribback, Silvia; Sailer, Verena; Böhning, Enrico; Günther, Julia; Merz, Jaqueline; Steinmüller, Frauke; Utpatel, Kirsten; Cigliano, Antonio; Peters, Kristin; Pilo, Maria Giulia; Evert, Matthias; Calvisi, Diego Francesco; Dombrowski, Frank
The Hippo pathway effector TAZ induces intrahepatic cholangiocarcinoma in mice and is ubiquitously activated in the human disease
2022-01-01 Cigliano, Antonio; Zhang, Shanshan; Ribback, Silvia; Steinmann, Sara; Sini, Marcella; Ament, Cindy E; Utpatel, Kirsten; Song, Xinhua; Wang, Jingxiao; Pilo, Maria G; Berger, Fabian; Wang, Haichuan; Tao, Junyan; Li, Xiaolei; Pes, Giovanni M; Mancarella, Serena; Giannelli, Gianluigi; Dombrowski, Frank; Evert, Matthias; Calvisi, Diego F; Chen, Xin; Evert, Katja
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A functional mammalian target of rapamycin complex 1 signaling is indispensable for c-Myc-driven hepatocarcinogenesis | 1-gen-2017 | Liu, Pin; Ge, Mengmeng; Hu, Junjie; Li, Xiaolei; Che, Li; Sun, Kun; Cheng, Lili; Huang, Yuedong; Pilo, Maria G; Cigliano, Antonio; Pes, Giovanni M; Pascale, Rosa M; Brozzetti, Stefania; Vidili, Gianpaolo; Porcu, Alberto; Cossu, Antonio; Palmieri, Giuseppe; Sini, Maria C; Ribback, Silvia; Dombrowski, Frank; Tao, Junyan; Calvisi, Diego F; Chen, Ligong; Chen, Xin | |
| Activated mutant forms of PIK3CA cooperate with RasV12 or c-Met to induce liver tumour formation in mice via AKT2/mTORC1 cascade | 1-gen-2016 | Wang, Chunmei; Che, Li; Hu, Junjie; Zhang, Shanshan; Jiang, Lijie; Latte, Gavinella; Demartis, Maria Ilaria; Tao, Junyan; Gui, Bing; Pilo, Maria Giulia; Ribback, Silvia; Dombrowski, Frank; Evert, Matthias; Calvisi, Diego Francesco; Chen, Xin | |
| Both de novo synthetized and exogenous fatty acids support the growth of hepatocellular carcinoma cells | 1-gen-2017 | Cao, Dan; Song, Xinhua; Che, Li; Li, Xiaolei; Pilo, Maria G.; Vidili, Gianpaolo; Porcu, Alberto; Solinas, Antonio; Cigliano, Antonio; Pes, Giovanni M.; Ribback, Silvia; Dombrowski, Frank; Chen, Xin; Li, Lei; Calvisi, Diego F. | |
| Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans | 1-gen-2019 | Che, Li; Chi, Wenna; Qiao, Yu; Zhang, Jie; Song, Xinhua; Liu, Ye; Li, Lei; Jia, Jiaoyuan; Pilo, Maria G.; Wang, Jingxiao; Cigliano, Antonio; Ma, Zhilong; Kuang, Wenhua; Tang, Zefang; Zhang, Zemin; Shui, Guanghou; Ribback, Silvia; Dombrowski, Frank; Evert, Matthias; Pascale, Rosa Maria; Cossu, Carla; Pes, Giovanni Mario; Osborne, Timothy F.; Calvisi, Diego F.; Chen, Xin; Chen, Ligong | |
| Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice | 1-gen-2016 | Hu, Junjie; Che, Li; Li, Lei; Pilo, Maria Giulia; Cigliano, Antonio; Ribback, Silvia; Li, Xiaolei; Latte, Gavinella; Mela, Marta; Evert, Matthias; Dombrowski, Frank; Zheng, Guohua; Chen, Xin; Calvisi, Diego Francesco | |
| Deregulated c-Myc requires a functional HSF1 for experimental and human hepatocarcinogenesis | 1-gen-2017 | Cigliano, Antonio; Pilo, Maria G.; Li, Lei; Latte, Gavinella; Szydlowska, Marta; Simile, Maria M.; Paliogiannis, Panagiotis; Che, Li; Pes, Giovanni M.; Palmieri, Giuseppe; Sini, Maria C.; Cossu, Antonio; Porcu, Alberto; Vidili, Gianpaolo; Seddaiu, Maria A.; Pascale, Rosa M.; Ribback, Silvia; Dombrowski, Frank; Chen, Xin; Calvisi, Diego F. | |
| Differential requirement for de novo lipogenesis in cholangiocarcinoma and hepatocellular carcinoma of mice and humans | 1-gen-2016 | Li, Lei; Che, Li; Tharp, Kevin M.; Park, Hyo Min; Pilo, Maria Giulia; Cao, Dan; Cigliano, Antonio; Latte, Gavinella; Xu, Zhong; Ribback, Silvia; Dombrowski, Frank; Evert, Matthias; Gores, Gregory J.; Stahl, Andreas; Calvisi, Diego Francesco; Chen, Xin | |
| Inhibition of HSF1 suppresses the growth of hepatocarcinoma cell lines in vitro and AKT-driven hepatocarcinogenesis in mice | 1-gen-2017 | Cigliano, Antonio; Wang, Chunmei; Pilo, Maria Giulia; Szydlowska, Marta; Brozzetti, Stefania; Latte, Gavinella; Pes, Giovanni Mario; Pascale, Rosa Maria; Seddaiu, Maria Antonietta; Vidili, Gianpaolo; Ribback, Silvia; Dombrowski, Frank; Evert, Matthias; Chen, Xin; Calvisi, Diego Francesco | |
| Inhibition of MELK Protooncogene as an Innovative Treatment for Intrahepatic Cholangiocarcinoma | 1-gen-2020 | Cigliano, Antonio; Pilo, Maria Giulia; Mela, Marta; Ribback, Silvia; Dombrowski, Frank; Pes, Giovanni Mario; Cossu, Antonio; Evert, Matthias; Calvisi, Diego Francesco; Utpatel, Kirsten | |
| Jagged 1 is a major Notch ligand along cholangiocarcinoma development in mice and humans | 1-gen-2016 | Che, L.; Fan, B.; Pilo, Maria Giulia; Xu, Z.; Liu, Yisu; Cigliano, Antonio; Cossu, Antonio; Palmieri, Giovanni; Pascale, Rosa Maria; Porcu, Alberto; Vidili, Gianpaolo; Serra, Marina; Dombrowski, F.; Ribback, S.; Calvisi, Diego Francesco; Chen, X. | |
| La Completa inibizione della via di segnale mTORC1 è necessaria per la soppressione dell’epatocancerogenesi indotta dall’iperespressione dei protooncogeni AKT e N-Ras nel topo | 24-feb-2014 | Pilo, Maria Giulia | |
| Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma | 1-gen-2017 | Che, Li; Pilo, Maria Giulia; Cigliano, Antonio; Latte, Gavinella; Simile, Maria Maddalena; Ribback, Silvia; Dombrowski, Frank; Evert, Matthias; Chen, Xin; Calvisi, Diego Francesco | |
| Oncogene-dependent addiction to carbohydrate-responsive element binding protein in hepatocellular carcinoma | 1-gen-2018 | Ribback, S; Che, L; Pilo, Mg; Cigliano, A; Latte, G; Pes, Gm; Porcu, A; Pascale, Rm; Li, L; Qiao, Yan; Dombrowski, F; Chen, X; Calvisi, Df | |
| Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice | 1-gen-2017 | Zhang, Shanshan; Song, Xinhua; Cao, Dan; Xu, Zhong; Fan, Biao; Che, Li; Hu, Junjie; Chen, Bin; Dong, Mingjie; Pilo, Maria G.; Cigliano, Antonio; Evert, Katja; Ribback, Silvia; Dombrowski, Frank; Pascale, Rosa M.; Cossu, Antonio; Vidili, Gianpaolo; Porcu, Alberto; Simile, Maria M.; Pes, Giovanni M.; Giannelli, Gianluigi; Gordan, John; Wei, Lixin; Evert, Matthias; Cong, Wenming; Calvisi, Diego F.; Chen, Xin | |
| Pathogenetic, Prognostic, and Therapeutic Role of Fatty Acid Synthase in Human Hepatocellular Carcinoma | 1-gen-2019 | Che, Li; Paliogiannis, Panagiotis; Cigliano, Antonio; Pilo, Maria G.; Chen, Xin; Calvisi, Diego F. | |
| Tankyrase inhibitors suppress hepatocellular carcinoma cell growth via modulating the Hippo cascade | 1-gen-2017 | Jia, J.; Qiao, Y.; Pilo, M. G.; Cigliano, A.; Liu, X.; Shao, Z.; Calvisi, D. F.; Chen, X. | |
| The Epidermal Growth Factor Receptor (EGFR) Inhibitor Gefitinib Reduces but Does Not Prevent Tumorigenesis in Chemical and Hormonal Induced Hepatocarcinogenesis Rat Models | 1-gen-2016 | Ribback, Silvia; Sailer, Verena; Böhning, Enrico; Günther, Julia; Merz, Jaqueline; Steinmüller, Frauke; Utpatel, Kirsten; Cigliano, Antonio; Peters, Kristin; Pilo, Maria Giulia; Evert, Matthias; Calvisi, Diego Francesco; Dombrowski, Frank | |
| The Hippo pathway effector TAZ induces intrahepatic cholangiocarcinoma in mice and is ubiquitously activated in the human disease | 1-gen-2022 | Cigliano, Antonio; Zhang, Shanshan; Ribback, Silvia; Steinmann, Sara; Sini, Marcella; Ament, Cindy E; Utpatel, Kirsten; Song, Xinhua; Wang, Jingxiao; Pilo, Maria G; Berger, Fabian; Wang, Haichuan; Tao, Junyan; Li, Xiaolei; Pes, Giovanni M; Mancarella, Serena; Giannelli, Gianluigi; Dombrowski, Frank; Evert, Matthias; Calvisi, Diego F; Chen, Xin; Evert, Katja |