Cellular Automata (CA), one of the most challenging computational paradigms in microscopic and macroscopic complex systems simulation, can be successfully addressed also by using a modified CA classical approach. In this contribution we discuss related aspects in applying the CANv2 approach in examples of micro and macro dynamics such as: superconductive devices and forest fire simulation. Advantages and limitations are introduced when both microscopic and macroscopic dynamics are taken into account justifying the introduction of hybrid components between single cellular automata, i.e. a network in which global behavior and local interactions can coexist with side effects in computational parallelism addressing.