Oral lesions may be found in patients with Crohn's disease (CD), in a percentage up to 20%. The aim of this study was to investigate a possible relationship between Mycobacterium avium subsp. paratuberculosis (MAP) and oral lesions in CD patients. 23 oral biopsies were examined performing IS900 Nested PCR; 9 of them were positive: 8 from CD patients and 1 from a control. Our purpose is to go on with this study, amplifying the number of subjects examined and testing subjects with oral lesions related to diseases other than CD to verify the specific association between MAP and oral lesions in CD patients.
Molecular identification of Mycobacterium avium subspecies paratuberculosis in oral biopsies of Crohn's disease patients / Molicotti, Paola; Scanu, Antonio Mario; Lumbau, Aurea Maria Immacolata; Cannas, Sara; Bua, Alessandra; Lugliè, P; Zanetti, Stefania Anna Lucia. - In: GUT PATHOGENS. - ISSN 1757-4749. - 5:1(2013), p. 18. [10.1186/1757-4749-5-18]
Molecular identification of Mycobacterium avium subspecies paratuberculosis in oral biopsies of Crohn's disease patients.
MOLICOTTI, Paola;SCANU, Antonio Mario;LUMBAU, Aurea Maria Immacolata;CANNAS, Sara;BUA, Alessandra;ZANETTI, Stefania Anna Lucia
2013-01-01
Abstract
Oral lesions may be found in patients with Crohn's disease (CD), in a percentage up to 20%. The aim of this study was to investigate a possible relationship between Mycobacterium avium subsp. paratuberculosis (MAP) and oral lesions in CD patients. 23 oral biopsies were examined performing IS900 Nested PCR; 9 of them were positive: 8 from CD patients and 1 from a control. Our purpose is to go on with this study, amplifying the number of subjects examined and testing subjects with oral lesions related to diseases other than CD to verify the specific association between MAP and oral lesions in CD patients.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
