Aim of this study was to compare two different anaesthetic combinations in healthy Red-Eared Slider Turtles. Twenty-four patients were randomly divided in two groups: TZBM, receiving tiletamine-zolazepam (10mg/kg) butorphanol (0,6mg/kg), medetomidine (0,2mg/kg); KBM, receiving ketamine (10mg/kg), butorphanol (0,6mg/kg) and medetomidine (0,2mg/kg). First signs and maximum level of sedation were timed. Heart rate (Hr), respiratory rate (Rr), temperature (T°) and depth of anaesthesia were recorded. After 60 minutes atipamezole (1mg/kg) was given and time recovery recorded. Quality of immobilization and behaviour were assessed during the procedure1. Statistical analysis included paired and unpaired t-tests, ANOVA and Kruskal–Wallis test. First signs and maximum level of sedation, were achieved respectively at 5± 1, 9±3 and 22,50±5 minutes in TDZM, at 6,50±1, 10±3 and 21±2,12 minutes in KZM. All patients showed apnea after protocol administration. After 60 minutes heart-rate decreased in both groups from 37bpm (Mean 10’ after induction), to 21bpm (p<0,05). Rectal temperature decreased of 1,1±0,1ºC, from initial 25ºC. Corneal, vent and pinch reflexes were maintained for all procedure. After atipamezole administration, spontaneous ventilation was achieved at 6±5,66 minutes in TZDM, followed by incoordination and ataxia in all subjects except one, while in KZM at 4±2,12 minutes (p<0,05). Three patients showed signs of incoordination. With KBM protocol all subjects were alert after 120 minutes, subjects in TZDM group appeared deeply sedated even at 480 minutes (p<0,05) Both protocols provide effective and safe chemical immobilization of patients. TZDM protocol is associated with incoordination, ataxia and prolonged recovery. Additional analgesia for surgery may be required.

Evaluation of chemical immobilisation with medetomidine-tiletamine-zolazepambutorphanol and medetomidine-ketamine-butorphanol in red-eared slider turtles (Trachemys scripta elegans) / Iannaccone M; Sanna Passino E; Campolo M; Bono L; Secci F; Columbano N. - xi:(2014), pp. 146-146. ((Intervento presentato al convegno International Conference on Diseases of Zoo and Wild Animals tenutosi a Warsaw/Poland nel 28-31/05/2014.

Evaluation of chemical immobilisation with medetomidine-tiletamine-zolazepambutorphanol and medetomidine-ketamine-butorphanol in red-eared slider turtles (Trachemys scripta elegans)

SANNA PASSINO, Eraldo;COLUMBANO, Nicolò
2014

Abstract

Aim of this study was to compare two different anaesthetic combinations in healthy Red-Eared Slider Turtles. Twenty-four patients were randomly divided in two groups: TZBM, receiving tiletamine-zolazepam (10mg/kg) butorphanol (0,6mg/kg), medetomidine (0,2mg/kg); KBM, receiving ketamine (10mg/kg), butorphanol (0,6mg/kg) and medetomidine (0,2mg/kg). First signs and maximum level of sedation were timed. Heart rate (Hr), respiratory rate (Rr), temperature (T°) and depth of anaesthesia were recorded. After 60 minutes atipamezole (1mg/kg) was given and time recovery recorded. Quality of immobilization and behaviour were assessed during the procedure1. Statistical analysis included paired and unpaired t-tests, ANOVA and Kruskal–Wallis test. First signs and maximum level of sedation, were achieved respectively at 5± 1, 9±3 and 22,50±5 minutes in TDZM, at 6,50±1, 10±3 and 21±2,12 minutes in KZM. All patients showed apnea after protocol administration. After 60 minutes heart-rate decreased in both groups from 37bpm (Mean 10’ after induction), to 21bpm (p<0,05). Rectal temperature decreased of 1,1±0,1ºC, from initial 25ºC. Corneal, vent and pinch reflexes were maintained for all procedure. After atipamezole administration, spontaneous ventilation was achieved at 6±5,66 minutes in TZDM, followed by incoordination and ataxia in all subjects except one, while in KZM at 4±2,12 minutes (p<0,05). Three patients showed signs of incoordination. With KBM protocol all subjects were alert after 120 minutes, subjects in TZDM group appeared deeply sedated even at 480 minutes (p<0,05) Both protocols provide effective and safe chemical immobilization of patients. TZDM protocol is associated with incoordination, ataxia and prolonged recovery. Additional analgesia for surgery may be required.
Evaluation of chemical immobilisation with medetomidine-tiletamine-zolazepambutorphanol and medetomidine-ketamine-butorphanol in red-eared slider turtles (Trachemys scripta elegans) / Iannaccone M; Sanna Passino E; Campolo M; Bono L; Secci F; Columbano N. - xi:(2014), pp. 146-146. ((Intervento presentato al convegno International Conference on Diseases of Zoo and Wild Animals tenutosi a Warsaw/Poland nel 28-31/05/2014.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11388/55612
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