Four-membered heterocycles (4-MH) with one or two heteroatoms are of great importance in medicinal chemistry and synthetic organic chemistry. This kind of scaffolds show peculiar structural features, related to the ring “puckering”, and biological properties. Our recent research efforts have been focused on the stereoselective synthesis and functionalization of some 4-MH such as azetidines, thietanes and oxazetidines.
Lithiation of 4-membered heterocycles as useful strategy for the preparation of new molecular scaffolds: addressing the regioselectivity in azetidines and thietanes / Pisano, Luisa; Zenzola, Marina; Trinchera, Piera; Carroccia, Laura; Falcicchio, Aurelia; Luisi, Renzo; Degennaro, Leonardo; Giovine, Arianna. - (2013). (Intervento presentato al convegno 35. Convegno della Divisione di chimica organica della Società Chimica Italiana).
Lithiation of 4-membered heterocycles as useful strategy for the preparation of new molecular scaffolds: addressing the regioselectivity in azetidines and thietanes
Pisano, Luisa;
2013-01-01
Abstract
Four-membered heterocycles (4-MH) with one or two heteroatoms are of great importance in medicinal chemistry and synthetic organic chemistry. This kind of scaffolds show peculiar structural features, related to the ring “puckering”, and biological properties. Our recent research efforts have been focused on the stereoselective synthesis and functionalization of some 4-MH such as azetidines, thietanes and oxazetidines.File | Dimensione | Formato | |
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