Cancer chemoteraphy continue to be an important research avenue. Combination chemotherapy using antineoplastic agents with different mechanisms of action is one method employed to combat this disease. Thus, a single molecule containing two functional groups, each with a different mechanism of action, also could prove beneficial in cancer treatment. Syntheses and biological results are reported.
Chromophore-modified bis-benzo[g]indolecarboxamides: synthesis and citotoxicity of bis-benzo[g]indazole-3-carboxamides and related compounds / Pinna, Gérard Aimé; Grella, Giuseppe Enrico; Mussinu, Jean-Mario; Murineddu, Gabriele; Pirisi, Maria Antonietta. - (2000). (Intervento presentato al convegno SardiniaChem 2000: giornata di studio dedicata alla chimica organica delle molecole biologicamente attive).
Chromophore-modified bis-benzo[g]indolecarboxamides: synthesis and citotoxicity of bis-benzo[g]indazole-3-carboxamides and related compounds
Pinna, Gérard Aimé;Grella, Giuseppe Enrico;Murineddu, Gabriele;Pirisi, Maria Antonietta
2000-01-01
Abstract
Cancer chemoteraphy continue to be an important research avenue. Combination chemotherapy using antineoplastic agents with different mechanisms of action is one method employed to combat this disease. Thus, a single molecule containing two functional groups, each with a different mechanism of action, also could prove beneficial in cancer treatment. Syntheses and biological results are reported.| File | Dimensione | Formato | |
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