Ferulic acid (4-hydroxy-3-methoxycinnamic acid) is an ubiquitous phenolic compound in plant tissues, and it constitutes a naturally occurring antioxidant compound found in many foods. Here we present different convenient ways to obtain five naturally occurring DiFAs via peroxidase-mediated oxidative coupling reactions or classic cross-coupling oxidations through a sustainable, safe and inexpensive chemistry. Such compounds arise from 5-5’, 8-8’, 8-5’ and 8-O-4’ coupling and some of them have been tested as potential inhibitors of micotoxin productionin vitro.

Straightforward preparation of biologically active dimers of ferulic acid / Migheli, Quirico; Scherm, Barbara; Pani, Giovanna; Dettori, Maria Antonietta; Delogu, Giovanna; Azara, Emanuela; Fabbri, Davide; Carta, Paola. - (2013). ((Intervento presentato al convegno 35. Convegno della Divisione di chimica organica della Società Chimica Italiana.

Straightforward preparation of biologically active dimers of ferulic acid

Migheli, Quirico;Scherm, Barbara;Pani, Giovanna;Delogu, Giovanna;Carta, Paola
2013-01-01

Abstract

Ferulic acid (4-hydroxy-3-methoxycinnamic acid) is an ubiquitous phenolic compound in plant tissues, and it constitutes a naturally occurring antioxidant compound found in many foods. Here we present different convenient ways to obtain five naturally occurring DiFAs via peroxidase-mediated oxidative coupling reactions or classic cross-coupling oxidations through a sustainable, safe and inexpensive chemistry. Such compounds arise from 5-5’, 8-8’, 8-5’ and 8-O-4’ coupling and some of them have been tested as potential inhibitors of micotoxin productionin vitro.
Straightforward preparation of biologically active dimers of ferulic acid / Migheli, Quirico; Scherm, Barbara; Pani, Giovanna; Dettori, Maria Antonietta; Delogu, Giovanna; Azara, Emanuela; Fabbri, Davide; Carta, Paola. - (2013). ((Intervento presentato al convegno 35. Convegno della Divisione di chimica organica della Società Chimica Italiana.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11388/263661
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