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EnglishDifferent methodologies are being developed, such as imaging, spectroscopy and electrochemistry, to study neurochemical dynamics in cell cultures or in intact brain [1-2]. One of these techniques involves the in-situ detection of biologically active molecules, including nitric oxide (NO) [3], glucose [4], glutamate (GLUT) [5-6] and lactate [1,7], in brain extracellular fluid (ECF), using implanted microsensors and biosensors. NO is a water-soluble free radical that readily diffuses through membranes and its actions in the CNS are largely studied.
Selective and sensitive poly-ortho-phenylenediamine-shielded microsensore and biosensors for in vivo neurochemical monitoring / Serra, Pier Andrea; Desole, Maria Speranza; Migheli, Rossana; Rocchitta, Gaia Giovanna Maria. - (2008). ((Intervento presentato al convegno SardiniaChem 2008: giornata di studio dedicata alla chimica organica delle molecole biologicamente attive.
| Titolo: | Selective and sensitive poly-ortho-phenylenediamine-shielded microsensore and biosensors for in vivo neurochemical monitoring | |
| Autori: | ||
| Data di pubblicazione: | 2008 | |
| Citazione: | Selective and sensitive poly-ortho-phenylenediamine-shielded microsensore and biosensors for in vivo neurochemical monitoring / Serra, Pier Andrea; Desole, Maria Speranza; Migheli, Rossana; Rocchitta, Gaia Giovanna Maria. - (2008). ((Intervento presentato al convegno SardiniaChem 2008: giornata di studio dedicata alla chimica organica delle molecole biologicamente attive. | |
| Abstract: | Different methodologies are being developed, such as imaging, spectroscopy and electrochemistry, to study neurochemical dynamics in cell cultures or in intact brain [1-2]. One of these techniques involves the in-situ detection of biologically active molecules, including nitric oxide (NO) [3], glucose [4], glutamate (GLUT) [5-6] and lactate [1,7], in brain extracellular fluid (ECF), using implanted microsensors and biosensors. NO is a water-soluble free radical that readily diffuses through membranes and its actions in the CNS are largely studied. | |
| Handle: | http://hdl.handle.net/11388/262535 | |
| Appare nelle tipologie: | 4.3 Poster |
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| File | Descrizione | Tipologia | Licenza | |
|---|---|---|---|---|
| Serra_P_ContrCongr_2008_Selective.pdf | Versione editoriale (versione finale pubblicata) | Non specificato | Open Access Visualizza/Apri |
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