Aim of this work is the preparation of spray-dried microspheres as drug delivery systems for Rokitamycin (RK), using chitosan (C) and its salt, chitosan glutamate (CG) to improve the dissolution rate of the drug. The work further aimed to investigate the effect of the type of chitosan and feed solution concentration on the microsphere properties.
Study of dissolution rate enhancement of poorly water soluble drug / Rassu, Giovanna; Giunchedi, Paolo; Gavini, Elisabetta; Spada, Giampiera. - (2008). (Intervento presentato al convegno SardiniaChem 2008: giornata di studio dedicata alla chimica organica delle molecole biologicamente attive).
Study of dissolution rate enhancement of poorly water soluble drug
Rassu, Giovanna;Giunchedi, Paolo;Gavini, Elisabetta;
2008-01-01
Abstract
Aim of this work is the preparation of spray-dried microspheres as drug delivery systems for Rokitamycin (RK), using chitosan (C) and its salt, chitosan glutamate (CG) to improve the dissolution rate of the drug. The work further aimed to investigate the effect of the type of chitosan and feed solution concentration on the microsphere properties.| File | Dimensione | Formato | |
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