The amides are one of the most important functional groups in organic chemistry and are present in many biologically active compounds with significant pharmacological properties. In this work a synthetic protocol for the direct synthesis of amides from benzyl alcohols and N-chloramines, prepared in situ, by the use of tert-butyl hydroperoxide (TBHP) and FeCl3as catalyst has been developed.
Iron-catalysed oxidative amidation of alcohols with amines / Porcheddu, Andrea; De Luca, Lidia Vera Giovanna; Gaspa, Silvia. - (2013). (Intervento presentato al convegno 35. Convegno della Divisione di chimica organica della Società Chimica Italiana).
Iron-catalysed oxidative amidation of alcohols with amines
Porcheddu, Andrea;De Luca, Lidia Vera Giovanna;Gaspa, Silvia
2013-01-01
Abstract
The amides are one of the most important functional groups in organic chemistry and are present in many biologically active compounds with significant pharmacological properties. In this work a synthetic protocol for the direct synthesis of amides from benzyl alcohols and N-chloramines, prepared in situ, by the use of tert-butyl hydroperoxide (TBHP) and FeCl3as catalyst has been developed.| File | Dimensione | Formato | |
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