Nickel compounds are well known as human carcinogens.We investigated the issue of Ni(II) binding within the histone octamer. Using histone sequences in conjuction with the structural data we identified a binding site for Ni(II) ions located in the N-terminal tail of the histone H4.
Nickel interaction with metal binding sequences of histone H4 / Zoroddu, M.A., Peana, M.F., Medici, S., Costa, M.. - (2004), pp. 91-91. (GIDRM XXXIV: 34. National congress on magnetic resonance ).
Nickel interaction with metal binding sequences of histone H4
Zoroddu, Maria Antonietta;Peana, Massimiliano Francesco;Medici, Serenella;
2004-01-01
Abstract
Nickel compounds are well known as human carcinogens.We investigated the issue of Ni(II) binding within the histone octamer. Using histone sequences in conjuction with the structural data we identified a binding site for Ni(II) ions located in the N-terminal tail of the histone H4.File in questo prodotto:
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