Animal physiological functions involve enzymes and cofactors. Many of these substances can not be synthesized by the body, but derive from the diet. An example are micronutrients, that strongly affect production performance, whose requirements are often met by the farmers by adding supplements to the diet. The aim of this study was to investigate the genetic variability of Italian sheep breeds searching for possible selective sweeps that harbor genes involved in the metabolism of micronutrients in. SNP A sample of 496 sheep belonging to 20 breeds farmed in Italy were genotyped with the Illumina Ovine 50K beadchip. Data were analysed by canonical discriminant analysis (CDA). Forty SNP located in regions of the genome containing loci involved in the metabolism of vitamins and minerals were detected. in particular, genes linked to the metabolism of vitamins and minerals such as Selenocysteine Lyase (SCLY), calcium sensing receptor (CASR), Solute Carrier Family 23 Member 1 (SLC23A1) and Thiamine Triphosphatase (THTPA) were highlighted.
Selection signatures scan in several Italian sheep breeds identifies genes influencing micronutrient metabolism / Sorbolini, S.; Dimauro, C.; Cellesi, M.; Pilla, F.; Macciotta, N. P. P.; Consortium., the BIOVITA. - (2018), p. 151. (Intervento presentato al convegno World Congress on Genetics Applied to Livestock Production tenutosi a Auckland, New Zealand nel 11–16 February 2018).
Selection signatures scan in several Italian sheep breeds identifies genes influencing micronutrient metabolism
S. Sorbolini;C. Dimauro;M. Cellesi;N. P. P. Macciotta
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2018-01-01
Abstract
Animal physiological functions involve enzymes and cofactors. Many of these substances can not be synthesized by the body, but derive from the diet. An example are micronutrients, that strongly affect production performance, whose requirements are often met by the farmers by adding supplements to the diet. The aim of this study was to investigate the genetic variability of Italian sheep breeds searching for possible selective sweeps that harbor genes involved in the metabolism of micronutrients in. SNP A sample of 496 sheep belonging to 20 breeds farmed in Italy were genotyped with the Illumina Ovine 50K beadchip. Data were analysed by canonical discriminant analysis (CDA). Forty SNP located in regions of the genome containing loci involved in the metabolism of vitamins and minerals were detected. in particular, genes linked to the metabolism of vitamins and minerals such as Selenocysteine Lyase (SCLY), calcium sensing receptor (CASR), Solute Carrier Family 23 Member 1 (SLC23A1) and Thiamine Triphosphatase (THTPA) were highlighted.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
