Background: Anaerobic bacteria are commonly associated with periodontal diseases. The present study aimed to test the clinical efficacy of the local oxygen therapy and the susceptibility of the anaerobic bacteria in adult patients with chronic periodontitis. This project was financed by the Region of Sardinia. Material and Methods: A prospective randomized clinical study was conducted in a group of 113 patients with chronic periodontitis. 56 subjects (mean age 43.30 ± 11.54) received scaling and root planing + local oxygen per ten consecutive days (case group) and 57 subjects (mean age 45.81 ± 8.36) only scaling and root planing (control group). Periodontal status was evaluated by the presence of bleeding on probing (BOP) and periodontal probing depth (PD). Subgingival plaque samples were taken and analyzed using PCR-real time technique for the levels of 6 periodontal bacteria. For each patient clinical and microbiological parameters were evaluated at baseline (t0), after 6-8 weeks (t1) and after 6 months (t2) from the last session of scaling and root planing. Results: At t1, mean PD (mm ± SEM) was reduced from 4.13 ± 0.66 to 3.3 ± 0.3 in the case group and from 3.98 ± 0.60 to 3.5 ± 0.4 in the control group (p<0.01). The mean BOP showed a significant reduction in both groups (p=0.03 between t0 and t1). At t2 the results are quite different in the two groups. The PD had a mean value of 3.5 ± 0.5 in the case group, and 3.6 ± 0.3 in control group. The mean BOP, however, had a slight increase in values (p=0.82 compared to t1 and p=0.02 compared to t0). At t1 reductions were observed for all the periodontal bacteria, mainly in the group treated with oxygen (p=0.04). At t2, the microbiological load of pathogenic bacteria had a rise compared to the values of t1. Conclusions: PD, BOP and the microbiological quality and quantity were significantly decreased in both of the groups. With the limitation of the present study, it’s possible to assert that local oxygen therapy could be a realistic non-surgical approach to the periodontal gum disease. Further studies are needed to test the efficacy of the therapeutic protocol in long term.

EFFECT OF LOCAL OXYGEN THERAPY IN CHRONIC PERIODONTAL DISEASE / Sacco, Gianluca; Sacco, Roberto; Anedda, Simona; Caria Gianni, Pietro; Lugliè, Pietrina Francesca; Campus, Guglielmo Giuseppe. - (2012). (Intervento presentato al convegno XIX Collegio dei Docenti di Odontoiatria tenutosi a Torino nel 12-14 Aprile).

EFFECT OF LOCAL OXYGEN THERAPY IN CHRONIC PERIODONTAL DISEASE

LUGLIÈ, Pietrina Francesca;CAMPUS, Guglielmo Giuseppe
2012-01-01

Abstract

Background: Anaerobic bacteria are commonly associated with periodontal diseases. The present study aimed to test the clinical efficacy of the local oxygen therapy and the susceptibility of the anaerobic bacteria in adult patients with chronic periodontitis. This project was financed by the Region of Sardinia. Material and Methods: A prospective randomized clinical study was conducted in a group of 113 patients with chronic periodontitis. 56 subjects (mean age 43.30 ± 11.54) received scaling and root planing + local oxygen per ten consecutive days (case group) and 57 subjects (mean age 45.81 ± 8.36) only scaling and root planing (control group). Periodontal status was evaluated by the presence of bleeding on probing (BOP) and periodontal probing depth (PD). Subgingival plaque samples were taken and analyzed using PCR-real time technique for the levels of 6 periodontal bacteria. For each patient clinical and microbiological parameters were evaluated at baseline (t0), after 6-8 weeks (t1) and after 6 months (t2) from the last session of scaling and root planing. Results: At t1, mean PD (mm ± SEM) was reduced from 4.13 ± 0.66 to 3.3 ± 0.3 in the case group and from 3.98 ± 0.60 to 3.5 ± 0.4 in the control group (p<0.01). The mean BOP showed a significant reduction in both groups (p=0.03 between t0 and t1). At t2 the results are quite different in the two groups. The PD had a mean value of 3.5 ± 0.5 in the case group, and 3.6 ± 0.3 in control group. The mean BOP, however, had a slight increase in values (p=0.82 compared to t1 and p=0.02 compared to t0). At t1 reductions were observed for all the periodontal bacteria, mainly in the group treated with oxygen (p=0.04). At t2, the microbiological load of pathogenic bacteria had a rise compared to the values of t1. Conclusions: PD, BOP and the microbiological quality and quantity were significantly decreased in both of the groups. With the limitation of the present study, it’s possible to assert that local oxygen therapy could be a realistic non-surgical approach to the periodontal gum disease. Further studies are needed to test the efficacy of the therapeutic protocol in long term.
2012
EFFECT OF LOCAL OXYGEN THERAPY IN CHRONIC PERIODONTAL DISEASE / Sacco, Gianluca; Sacco, Roberto; Anedda, Simona; Caria Gianni, Pietro; Lugliè, Pietrina Francesca; Campus, Guglielmo Giuseppe. - (2012). (Intervento presentato al convegno XIX Collegio dei Docenti di Odontoiatria tenutosi a Torino nel 12-14 Aprile).
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11388/139383
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