Haemoglobin (Hb) phenotypes have been studied in 100 wild European mouflons living on the island of Sardinia by means of isoelectric focusing (pH 6.7-7.7 range) of the native tetramers, acid-urea-Triton gel-electrophoresis, and reversed-phase HPLC of globin chains. The result indicates the presence of two beta-globin alleles one of which, corresponding to the beta-B, being the most common (f = 0.94). None were carriers of the earlier described Hb A. The new Hb was provisionally named Hb M. Severely anaemic mouflons were able to synthesize Hb C at expense of the Hb B alone, thus suggesting structural and physiological homologies between mouflon beta-B and sheep beta-A globin genes, and between the newly observed beta-M allele and the beta-B of the domestic Sardinian sheep.
Scheda prodotto non validato
Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo
|Titolo:||HEMOGLOBIN PHENOTYPES OF THE WILD EUROPEAN MOUFLON SHEEP LIVING ON THE ISLAND OF SARDINIA|
|Data di pubblicazione:||1991|
|Appare nelle tipologie:||1.1 Articolo in rivista|