Efficient oxidation of primary alcohols to the corresponding carboxylic acids can be carried out at room temperature and in acetone/water, using trichloroisocyanuric acid (TCCA) in the presence of catalytic TEMPO. The mild conditions of this procedure and the total absence of any transition metal make this reaction suitable for safe laboratory use. A possible mechanism is presented and discussed.

Trichloroisocyanuric/TEMPO Oxidation of Alcohols under Mild Conditions: A Close Investigation / DE LUCA, Lidia Vera Giovanna; Giacomelli, Giampaolo; Masala, M.; Porcheddu, Andrea. - In: JOURNAL OF ORGANIC CHEMISTRY. - ISSN 0022-3263. - 68:12(2003), pp. 4999-5001. [10.1021/jo034276b]

Trichloroisocyanuric/TEMPO Oxidation of Alcohols under Mild Conditions: A Close Investigation

DE LUCA, Lidia Vera Giovanna;GIACOMELLI, Giampaolo;PORCHEDDU, Andrea
2003-01-01

Abstract

Efficient oxidation of primary alcohols to the corresponding carboxylic acids can be carried out at room temperature and in acetone/water, using trichloroisocyanuric acid (TCCA) in the presence of catalytic TEMPO. The mild conditions of this procedure and the total absence of any transition metal make this reaction suitable for safe laboratory use. A possible mechanism is presented and discussed.
2003
Trichloroisocyanuric/TEMPO Oxidation of Alcohols under Mild Conditions: A Close Investigation / DE LUCA, Lidia Vera Giovanna; Giacomelli, Giampaolo; Masala, M.; Porcheddu, Andrea. - In: JOURNAL OF ORGANIC CHEMISTRY. - ISSN 0022-3263. - 68:12(2003), pp. 4999-5001. [10.1021/jo034276b]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11388/63085
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