A 58-year-old man was admitted because of respiratory failure, episodic fever with chilling, cough, malaise, fatigue, myalgia and weight loss lasting for at least one month. Chest x-rays and CT scan of the chest showed bilateral pulmonary consolidations in upper lobes, the left lower lobe, and mediastinal lymphadenopathy. Bronchoscopy with cytology was unremarkable. A needle CT-guided lung biopsy documented an inflammatory pseudotumor, lymphoplasmacytic type. Serology showed high titer antibodies to phase II Coxiella burnetii infection. Therapy with doxycycline and hydroxychloroquine for three months led to a complete resolution of symptoms and radiological findings, and a marked decrease in titers to Q fever.
Pulmonary inflammatory pseudotumor due to Coxiella burnetii. Case report and literature review / Polo, M. F.; Mastrandrea, S.; Santoru, L.; Arcadu, A.; Masala, G.; Marras, V.; Bagella, G.; Sechi, M. M.; Tanda, F.; Pirina, P.. - In: MICROBES AND INFECTION. - ISSN 1286-4579. - 17:11-12(2015), pp. 795-798. [10.1016/j.micinf.2015.08.008]
Pulmonary inflammatory pseudotumor due to Coxiella burnetii. Case report and literature review.
Tanda, F.;Pirina, P.
2015-01-01
Abstract
A 58-year-old man was admitted because of respiratory failure, episodic fever with chilling, cough, malaise, fatigue, myalgia and weight loss lasting for at least one month. Chest x-rays and CT scan of the chest showed bilateral pulmonary consolidations in upper lobes, the left lower lobe, and mediastinal lymphadenopathy. Bronchoscopy with cytology was unremarkable. A needle CT-guided lung biopsy documented an inflammatory pseudotumor, lymphoplasmacytic type. Serology showed high titer antibodies to phase II Coxiella burnetii infection. Therapy with doxycycline and hydroxychloroquine for three months led to a complete resolution of symptoms and radiological findings, and a marked decrease in titers to Q fever.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
