The stability of ketorolac tromethamine was investigated in acid (0.5M HCl) and alkaline conditions (0.5M NaOH), using the same procedure reported by Devarajan et al. [2]. The acid and base degradation products were identified by liquid chromatography–mass spectrometry (LC–MS).
Acid and base degraded products of ketorolac / Salaris, M.; Nieddu, M.; Rubattu, N.; Testa, C.; Luongo, E.; Rimoli, M. G.; Boatto, Gianpiero. - In: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. - ISSN 0731-7085. - 52:2(2010), pp. 320-322. [10.1016/j.jpba.2010.01.031]
Acid and base degraded products of ketorolac
M. NIEDDU;BOATTO, Gianpiero
2010-01-01
Abstract
The stability of ketorolac tromethamine was investigated in acid (0.5M HCl) and alkaline conditions (0.5M NaOH), using the same procedure reported by Devarajan et al. [2]. The acid and base degradation products were identified by liquid chromatography–mass spectrometry (LC–MS).File in questo prodotto:
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