Myxomatous mitral valve disease (MMVD) is the most common cardiac disease in dogs. It varies from dogs without clinical signs to those developing left-sided congestive heart failure, leading to death. Cavalier King Charles Spaniels (CKCSs) are particularly susceptible to MMVD. We hypothesised that within the elderly CKCS population, there is a sub-cohort of MMVD-affected dogs that do not have cardiac remodelling. The objectives of the present study were (i) to determine the prevalence and the degree of cardiac remodelling associated with MMVD; and (ii) assess the effect of age, gender, and body weight on echocardiographic status in a population of aged CKCSs. A total of 126 CKCSs ≥ 8 years old were prospectively included. They all had a physical and echocardiographic examination. A systolic murmur was detected in 89% of dogs; the presence of clinical signs was reported in 19% of them; and echocardiographic evidence of MMVD was described in 100%. Despite the high prevalence, 44.4% of the dogs were clear of echocardiographic signs of cardiac remodelling. Age was significantly associated with the presence and severity of cardiac remodelling and mitral valve prolapse. Our results showed that a proportion of elderly CKCS with confirmed MMVD did not undergo advanced stages of this pathology.

Clinical and echocardiographic findings in an aged population of cavalier king charles spaniels / Ramos, J. P.; Corda, A.; Swift, S.; Saderi, L.; Oliver, G. D. L. F.; Corcoran, B.; Summers, K. M.; French, A. T.. - In: ANIMALS. - ISSN 2076-2615. - 11:4(2021), p. 949. [10.3390/ani11040949]

Clinical and echocardiographic findings in an aged population of cavalier king charles spaniels

Corda A.
;
Saderi L.;
2021-01-01

Abstract

Myxomatous mitral valve disease (MMVD) is the most common cardiac disease in dogs. It varies from dogs without clinical signs to those developing left-sided congestive heart failure, leading to death. Cavalier King Charles Spaniels (CKCSs) are particularly susceptible to MMVD. We hypothesised that within the elderly CKCS population, there is a sub-cohort of MMVD-affected dogs that do not have cardiac remodelling. The objectives of the present study were (i) to determine the prevalence and the degree of cardiac remodelling associated with MMVD; and (ii) assess the effect of age, gender, and body weight on echocardiographic status in a population of aged CKCSs. A total of 126 CKCSs ≥ 8 years old were prospectively included. They all had a physical and echocardiographic examination. A systolic murmur was detected in 89% of dogs; the presence of clinical signs was reported in 19% of them; and echocardiographic evidence of MMVD was described in 100%. Despite the high prevalence, 44.4% of the dogs were clear of echocardiographic signs of cardiac remodelling. Age was significantly associated with the presence and severity of cardiac remodelling and mitral valve prolapse. Our results showed that a proportion of elderly CKCS with confirmed MMVD did not undergo advanced stages of this pathology.
2021
Clinical and echocardiographic findings in an aged population of cavalier king charles spaniels / Ramos, J. P.; Corda, A.; Swift, S.; Saderi, L.; Oliver, G. D. L. F.; Corcoran, B.; Summers, K. M.; French, A. T.. - In: ANIMALS. - ISSN 2076-2615. - 11:4(2021), p. 949. [10.3390/ani11040949]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11388/246037
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