Impact of renin-angiotensin system inhibitors on mortality during the COVID Pandemic among STEMI patients undergoing mechanical reperfusion: Insight from an international STEMI registry

De Luca, Giuseppe; Cercek, Miha; Okkels Jensen, Lisette; Bushljetikj, Oliver; Calmac, Lucian; Johnson, Tom; Gracida Blancas, Montserrat; Ganyukov, Vladimir; Wojakowski, Wojtek; von Birgelen, Clemens; Ijsselmuiden, Alexander; Tuccillo, Bernardo; Versaci, Francesco; Ten Berg, Jurrien; Laine, Mika; Berkout, Tim; Casella, Gianni; Kala, Petr; López Ledesma, Bernabé; Becerra, Victor; Padalino, Roberto; Santucci, Andrea; Carrillo, Xavier; Scoccia, Alessandra; Amoroso, Giovanni; Lux, Arpad; Kovarnik, Tomas; Davlouros, Periklis; Gabrielli, Gabriele; Flores Rios, Xacobe; Bakraceski, Nikola; Levesque, Sébastien; Guiducci, Vincenzo; Kidawa, Michał; Marinucci, Lucia; Zilio, Filippo; Galasso, Gennaro; Fabris, Enrico; Menichelli, Maurizio; Manzo, Stephane; Caiazzo, Gianluca; Moreu, Jose; Sanchis Forés, Juan; Donazzan, Luca; Vignali, Luigi; Teles, Rui; Agostoni, Pierfrancesco; Bosa Ojeda, Francisco; Lehtola, Heidi; Camacho-Freiere, Santiago; Kraaijeveld, Adriaan; Antti, Ylitalo; Visconti, Gabriella; Lozano Martínez-Luengas, Iñigo; Scheller, Bruno; Alexopulos, Dimitrios; Moreno, Raul; Kedhi, Elvin; Uccello, Giuseppe; Faurie, Benjamin; Gutierrez Barrios, Alejandro; Scotto Di Uccio, Fortunato; Wilbert, Bor; Cortese, Giuliana; Dirksen, Maurits T; Parodi, Guido; Verdoia, Monica

doi:10.1016/j.biopha.2021.111469

Concerns have been raised on a potential interaction between renin-angiotensin system inhibitors (RASI) and the susceptibility to coronavirus disease 2019 (COVID-19). No data have been so far reported on the prognostic impact of RASI in patients suffering from ST-elevation myocardial infarction (STEMI) during COVID-19 pandemic, which was the aim of the present study.

Impact of renin-angiotensin system inhibitors on mortality during the COVID Pandemic among STEMI patients undergoing mechanical reperfusion: Insight from an international STEMI registry / De Luca, Giuseppe; Cercek, Miha; Okkels Jensen, Lisette; Bushljetikj, Oliver; Calmac, Lucian; Johnson, Tom; Gracida Blancas, Montserrat; Ganyukov, Vladimir; Wojakowski, Wojtek; von Birgelen, Clemens; Ijsselmuiden, Alexander; Tuccillo, Bernardo; Versaci, Francesco; Ten Berg, Jurrien; Laine, Mika; Berkout, Tim; Casella, Gianni; Kala, Petr; López Ledesma, Bernabé; Becerra, Victor; Padalino, Roberto; Santucci, Andrea; Carrillo, Xavier; Scoccia, Alessandra; Amoroso, Giovanni; Lux, Arpad; Kovarnik, Tomas; Davlouros, Periklis; Gabrielli, Gabriele; Flores Rios, Xacobe; Bakraceski, Nikola; Levesque, Sébastien; Guiducci, Vincenzo; Kidawa, Michał; Marinucci, Lucia; Zilio, Filippo; Galasso, Gennaro; Fabris, Enrico; Menichelli, Maurizio; Manzo, Stephane; Caiazzo, Gianluca; Moreu, Jose; Sanchis Forés, Juan; Donazzan, Luca; Vignali, Luigi; Teles, Rui; Agostoni, Pierfrancesco; Bosa Ojeda, Francisco; Lehtola, Heidi; Camacho-Freiere, Santiago; Kraaijeveld, Adriaan; Antti, Ylitalo; Visconti, Gabriella; Lozano Martínez-Luengas, Iñigo; Scheller, Bruno; Alexopulos, Dimitrios; Moreno, Raul; Kedhi, Elvin; Uccello, Giuseppe; Faurie, Benjamin; Gutierrez Barrios, Alejandro; Scotto Di Uccio, Fortunato; Wilbert, Bor; Cortese, Giuliana; Dirksen, Maurits T; Parodi, Guido; Verdoia, Monica. - In: BIOMÉDECINE & PHARMACOTHÉRAPIE. - ISSN 0753-3322. - 138:(2021), p. 111469. [10.1016/j.biopha.2021.111469]