Engineered nanoparticles (NPs) to specifically deliver payload therapeutics to target cells involved in pathophysiological processes seem to offer a powerful strategy to overcome intrinsic limitations of drugs. In this Viewpoint we disclose the synergistic potential between medicinal chemistry and nanomedicine to exploit the "targeting concept"in developing effective nanotherapeutics, as well as the challenges and limitations that should be considered in pursuing their clinical translation, especially toward precision medicine.

Therapeutic Potential of Targeted Nanoparticles and Perspective on Nanotherapies / Sanna, V.; Sechi, M.. - In: ACS MEDICINAL CHEMISTRY LETTERS. - ISSN 1948-5875. - 11:6(2020), pp. 1069-1073. [10.1021/acsmedchemlett.0c00075]

Therapeutic Potential of Targeted Nanoparticles and Perspective on Nanotherapies

Sanna V.;Sechi M.
2020-01-01

Abstract

Engineered nanoparticles (NPs) to specifically deliver payload therapeutics to target cells involved in pathophysiological processes seem to offer a powerful strategy to overcome intrinsic limitations of drugs. In this Viewpoint we disclose the synergistic potential between medicinal chemistry and nanomedicine to exploit the "targeting concept"in developing effective nanotherapeutics, as well as the challenges and limitations that should be considered in pursuing their clinical translation, especially toward precision medicine.
2020
Therapeutic Potential of Targeted Nanoparticles and Perspective on Nanotherapies / Sanna, V.; Sechi, M.. - In: ACS MEDICINAL CHEMISTRY LETTERS. - ISSN 1948-5875. - 11:6(2020), pp. 1069-1073. [10.1021/acsmedchemlett.0c00075]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11388/239441
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