In thirty-two patients, divided into four groups: Normal, G-6-PD deficient, Ã-thalaxemic heterozygote and carriers of both anomalies, the variations in erythrocyte GSH were studied after incubation with APH and a nonsteroidal anti-inflammatory drug: Tolmetin sodium. The results obtained show a considerable fall in GSH after incubation with APH above all in the G-6-PD deficient patients and in the carriers of both anomalies. On the other hand, after incubation with the drug under examination there were no significant variations in the erythrocyte GSH. © 1979, SAGE Publications. All rights reserved.
Tolmetin and G-6-PD Erythrocyte Deficiency: Research in Vitro / Passiu, G.; Piras, M. G.; Perpignano, G.; Ibba, G.; Carcassi, U.. - In: JOURNAL OF INTERNATIONAL MEDICAL RESEARCH. - ISSN 0300-0605. - 7:5(1979), pp. 351-353. [10.1177/030006057900700503]
Tolmetin and G-6-PD Erythrocyte Deficiency: Research in Vitro
Passiu, G.;
1979-01-01
Abstract
In thirty-two patients, divided into four groups: Normal, G-6-PD deficient, Ã-thalaxemic heterozygote and carriers of both anomalies, the variations in erythrocyte GSH were studied after incubation with APH and a nonsteroidal anti-inflammatory drug: Tolmetin sodium. The results obtained show a considerable fall in GSH after incubation with APH above all in the G-6-PD deficient patients and in the carriers of both anomalies. On the other hand, after incubation with the drug under examination there were no significant variations in the erythrocyte GSH. © 1979, SAGE Publications. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.