OBJECTIVES: We have investigated on the levels of homocysteine linked to LDL in acute myocardial infarction patients. DESIGN AND METHODS: We used capillary electrophoresis to measure LDL-bound thiols in 16 AMI individuals and 32 healthy volunteers. RESULTS: We found a significant increase of apo-B homocysteine and cysteine levels in LDL fraction of AMI subjects. CONCLUSIONS: Our findings suggest that also LDL S-homocysteinylation may be considered among the markers for the CVD risk evaluation.

Low density lipoprotein S-homocysteinylation is increased in acute myocardial infarction patients / Zinellu, Angelo; Sotgia, S; Scanu, B; Deiana, Luca; Talanas, G; Terrosu, P; Carru, Ciriaco. - In: CLINICAL BIOCHEMISTRY. - ISSN 0009-9120. - 45:4-5(2012), pp. 359-362. [10.1016/j.clinbiochem.2011.12.017]

Low density lipoprotein S-homocysteinylation is increased in acute myocardial infarction patients

ZINELLU, Angelo;Sotgia S;DEIANA, Luca;CARRU, Ciriaco
2012-01-01

Abstract

OBJECTIVES: We have investigated on the levels of homocysteine linked to LDL in acute myocardial infarction patients. DESIGN AND METHODS: We used capillary electrophoresis to measure LDL-bound thiols in 16 AMI individuals and 32 healthy volunteers. RESULTS: We found a significant increase of apo-B homocysteine and cysteine levels in LDL fraction of AMI subjects. CONCLUSIONS: Our findings suggest that also LDL S-homocysteinylation may be considered among the markers for the CVD risk evaluation.
2012
Low density lipoprotein S-homocysteinylation is increased in acute myocardial infarction patients / Zinellu, Angelo; Sotgia, S; Scanu, B; Deiana, Luca; Talanas, G; Terrosu, P; Carru, Ciriaco. - In: CLINICAL BIOCHEMISTRY. - ISSN 0009-9120. - 45:4-5(2012), pp. 359-362. [10.1016/j.clinbiochem.2011.12.017]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11388/156404
Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 11
  • ???jsp.display-item.citation.isi??? 9
social impact